PDB ID 1tl1 sequence information (FASTA format)
Descriptor CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW451211
Title CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW451211
Functional Keywords HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, GW451211, DRUG DESIGN, TRANSFERASE
Biological source Human immunodeficiency virus 1
Cellular location
[UNP - P04585 ]
Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential)
Total number of polymer chains 2
Total molecular weight 116632.2 (the details in Structural Details Page )
Authors Hopkins, A.L. , Ren, J. , Stuart, D.I. , Stammers, D.K.
(deposition date : 2004-06-09, release date : 2004-12-07)
Primary citation Hopkins, A.L. , Ren, J. , Milton, J. , Hazen, R.J. , Chan, J.H. , Stuart, D.I. , Stammers, D.K.J.Med.Chem. ,
47:5912 - 5922, 2004.(PubMed : 15537346) (DOI: 10.1021/jm040071z)
Experimental method X-RAY DIFFRACTION ( 2.90[Å] )
Other Database Information
