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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1xsl  sequence information (FASTA format)   
RELATED PDB ID1xsn, 1xsp
Descriptor5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3'/ 5'-D(*GP*TP*GP*CP*GP*C)-3'/ 5'-D(P*GP*CP*CP*G)-3'
TitleCrystal Structure of human DNA polymerase lambda in complex with a one nucleotide DNA gap
Functional KeywordsDNA POLYMERASE LAMBDA, Protein-DNA complex, Helix-hairpin-helix, TRANSFERASE/DNA COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q9UGP5] Nucleus
Organ source [UNP - Q9UGP5] Placenta
[UNP - Q9UGP5] Lymph node
[UNP - Q9UGP5] Testis
[UNP - Q9UGP5] Mammary gland
Total number of polymer chains16
Total molecular weight175713.1 (the details in Structural Details Page)
AuthorsGarcia-Diaz, M. , Bebenek, K. , Krahn, J.M. , Kunkel, T.A. , Pedersen, L.C. (deposition date : 2004-10-19, release date : 2005-01-18)
Primary citationGarcia-Diaz, M. , Bebenek, K. , Krahn, J.M. , Kunkel, T.A. , Pedersen, L.C.
A closed conformation for the Pol lambda catalytic cycle.
Nat.Struct.Mol.Biol., 12:97 - 98, 2005.(PubMed : 15608652)  (DOI: 10.1038/nsmb876)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9UGP5 ) , eF-site , PISA