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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1xxv  sequence information (FASTA format)   
RELATED PDB ID1xxp, 1qz0
DescriptorProtein-tyrosine phosphatase yopH (E.C.3.1.3.48), Epidermal growth factor receptor derived peptide
TitleYersinia YopH (residues 163-468) binds phosphonodifluoromethyl-Phe containing hexapeptide at two sites
Functional Keywordscatalytic domain, phosphotyrosine-binding sites, substrate targeting, HYDROLASE
Biological sourceYersinia enterocolitica
Cellular location [UNP - P15273] Secreted
Total number of polymer chains6
Total molecular weight70390.8 (the details in Structural Details Page)
AuthorsIvanov, M.I. , Stuckey, J.A. , Schubert, H.L. , Saper, M.A. , Bliska, J.B. (deposition date : 2004-11-08, release date : 2005-03-22)
Primary citationIvanov, M.I. , Stuckey, J.A. , Schubert, H.L. , Saper, M.A. , Bliska, J.B.
Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence
Mol.Microbiol., 55:1346 - 1356, 2005.(PubMed : 15720545)  (DOI: 10.1111/j.1365-2958.2005.04477.x)
Experimental methodX-RAY DIFFRACTION ( 2.5[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P15273 ) , eF-site , KEGG ( EC 3.1.3.48 ) , PISA