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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID2h6u  sequence information (FASTA format)   
RELATED PDB ID2h1x, 1f41
Descriptor5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) (E.C.3.5.2.17)
TitleCrystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein)
Functional Keywords5-HYDROXYISOURATE HYDROLASE, TRP, URIC ACID DEGRADATION, ALLANTOIN
Biological sourceDanio rerio (zebrafish)
Total number of polymer chains8
Total molecular weight106081.6 (the details in Structural Details Page)
AuthorsZanotti, G. , Cendron, L. , Folli, C. , Ramazzina, I. , Percudani, R. , Berni, R. (deposition date : 2006-06-01, release date : 2006-10-31)
Primary citationZanotti, G. , Cendron, L. , Ramazzina, I. , Folli, C. , Percudani, R. , Berni, R.
Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363:1 - 9, 2006.(PubMed : 16952372)  (DOI: 10.1016/j.jmb.2006.07.079)
Experimental methodX-RAY DIFFRACTION ( 1.70[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q06S87 ) , eF-site , KEGG ( EC 3.5.2.17 ) , PISA