English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2b1v  sequence information (FASTA format)   
RELATED PDB ID1zky, 2b1z
DescriptorHUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH OBCP-1M AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
TitleHuman estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide
Functional KeywordsESTROGEN RECEPTOR, LBD, GRIP PEPTIDE, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P03372] Nucleus
Organ source [UNP - P03372] Mammary gland
[UNP - P03372] Mammary carcinoma
[UNP - Q15596] Placenta
[UNP - Q15596] Epithelium
[UNP - Q15596] Testis
Total number of polymer chains4
Total molecular weight62736.4 (the details in Structural Details Page)
AuthorsRajan, S.S. , Hsieh, R.W. , Sharma, S.K. , Greene, G.L. (deposition date : 2005-09-16, release date : 2006-05-09)
Primary citationHsieh, R.W. , Rajan, S.S. , Sharma, S.K. , Guo, Y. , Desombre, E.R. , Mrksich, M. , Greene, G.L.
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
J.Biol.Chem., 281:17909 - 17919, 2006.(PubMed : 16648639)  (DOI: 10.1074/jbc.M513684200)
Experimental methodX-RAY DIFFRACTION ( 1.80[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P03372, Q15596 ) , eF-site , PISA