PDB ID 2b1v sequence information (FASTA format)
RELATED PDB ID 1zky , 2b1z
Descriptor HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH OBCP-1M AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
Title Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide
Functional Keywords ESTROGEN RECEPTOR, LBD, GRIP PEPTIDE, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX
Biological source Homo sapiens
(human)
Cellular location
[UNP - P03372 ]
Nucleus
Organ source
[UNP - P03372 ]
Mammary gland
[UNP - P03372 ]
Mammary carcinoma
[UNP - Q15596 ]
Placenta
[UNP - Q15596 ]
Epithelium
[UNP - Q15596 ]
Testis
Total number of polymer chains 4
Total molecular weight 62736.4 (the details in Structural Details Page )
Authors Rajan, S.S. , Hsieh, R.W. , Sharma, S.K. , Greene, G.L.
(deposition date : 2005-09-16, release date : 2006-05-09)
Primary citation Hsieh, R.W. , Rajan, S.S. , Sharma, S.K. , Guo, Y. , Desombre, E.R. , Mrksich, M. , Greene, G.L. Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.
J.Biol.Chem. ,
281:17909 - 17919, 2006.(PubMed : 16648639) (DOI: 10.1074/jbc.M513684200)
Experimental method X-RAY DIFFRACTION ( 1.80[Å] )
Other Database Information