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MineSummary [2c37]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2c37  sequence information (FASTA format)   
RELATED PDB ID2br2, 2c38, 2c39
DescriptorPROBABLE EXOSOME COMPLEX EXONUCLEASE 2 (E.C.3.1.13.-), PROBABLE EXOSOME COMPLEX EXONUCLEASE 1 (E.C.3.1.13.-)
TitleRNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA
Functional KeywordsEXOSOME, RRP41, RRP42, EXORIBONUCLEASE, RNA DEGRADATION, ARCHAEAL, HYDROLASE
Biological sourceSULFOLOBUS SOLFATARICUS
Cellular location [UNP - Q9UXC0] Cytoplasm (Potential)
Total number of polymer chains24
Total molecular weight702876.1 (the details in Structural Details Page)
AuthorsLorentzen, E. , Conti, E. (deposition date : 2005-10-04, release date : 2005-11-23)
Primary citationLorentzen, E. , Conti, E.
Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20:473 - 481, 2005.(PubMed : 16285928)  (DOI: 10.1016/j.molcel.2005.10.020)
Experimental methodX-RAY DIFFRACTION ( 2.80[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9UXC0, Q9UXC2 ) , eF-site , KEGG (EC 3.1.13.- ) , PISA