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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID2fpv  sequence information (FASTA format)   
RELATED PDB ID2bxv, 2fpt, 2fpy, 2fqi
DescriptorDihydroorotate dehydrogenase, mitochondrial (E.C.1.3.3.1)
TitleDual binding mode of a novel series of DHODH inhibitors
Functional Keywordsprotein inhibitor compley, OXIDOREDUCTASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q02127] Mitochondrion inner membrane
Organ source [UNP - Q02127] Testis
[UNP - Q02127] Skin
Total number of polymer chains1
Total molecular weight44708.8 (the details in Structural Details Page)
AuthorsBaumgartner, R. , Leban, J. (deposition date : 2006-01-17, release date : 2007-01-23)
Primary citationBaumgartner, R. , Walloschek, M. , Kralik, M. , Gotschlich, A. , Tasler, S. , Mies, J. , Leban, J.
Dual binding mode of a novel series of DHODH inhibitors.
J.Med.Chem., 49:1239 - 1247, 2006.(PubMed : 16480261)  (DOI: 10.1021/jm0506975)
Experimental methodX-RAY DIFFRACTION ( 1.800[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q02127 ) , eF-site , KEGG ( EC 1.3.3.1 ) , PISA