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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1n7r  sequence information (FASTA format)   
RELATED PDB ID1c82, 1n7n, 1n7o, 1n7p, 1n7q
DescriptorHYALURONIDASE (E.C.4.2.2.1)
TitleStreptococcus pneumoniae Hyaluronate Lyase W291A/W292A/F343V Mutant complex with hexasaccharide hyaluronan
Functional Keywordsprotein mutant, LYASE
Biological sourceStreptococcus pneumoniae
Total number of polymer chains2
Total molecular weight83196.1 (the details in Structural Details Page)
AuthorsNukui, M. , Taylor, K.B. , McPherson, D.T. , Shigenaga, M. , Jedrzejas, M.J. (deposition date : 2002-11-16, release date : 2002-12-31)
Primary citationNukui, M. , Taylor, K.B. , McPherson, D.T. , Shigenaga, M.K. , Jedrzejas, M.J.
The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
J.Biol.Chem., 278:3079 - 3088, 2003.(PubMed : 12446724)  (DOI: 10.1074/jbc.M204999200)
Experimental methodX-RAY DIFFRACTION ( 2.20[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , GenBank/DDBJ/EMBL (GB - 437705) , eF-site , KEGG ( EC 4.2.2.1 ) , PISA