English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1d8d  sequence information (FASTA format)   
RELATED PDB ID1ft1, 1ft2, 1d8e
Descriptorfarnesyltranserase (alpha subunit)/farnesyltranserase (beta subunit)/K-RAS4B PEPTIDE SUBSTRATE
TitleCO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION
Functional KeywordsFTASE, PFT, PFTASE, FARNESYLTRANSFERASE, FARNESYL TRANSFERASE, CAAX, RAS, CANCER
Biological sourceRattus norvegicus (Norway rat)
Cellular location [UNP - P01116] Cell membrane; Lipid-anchor; Cytoplasmic side
Organ sourceBRAIN
Total number of polymer chains3
Total molecular weight94781 (the details in Structural Details Page)
AuthorsLong, S.B. , Casey, P.J. , Beese, L.S. (deposition date : 1999-10-22, release date : 2000-02-09)
Primary citationLong, S.B. , Casey, P.J. , Beese, L.S.
The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 Angstroms resolution ternary complex structures.
Structure, 8:209 - 222, 2000.(PubMed : 10673434)  (DOI: 10.1016/S0969-2126(00)00096-4)
Experimental methodX-RAY DIFFRACTION ( 2.00[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q04631, Q02293, P01116 ) , eF-site , KEGG ( EC 2.5.1.21 ) , PISA