PDB ID 1d8d sequence information (FASTA format)
RELATED PDB ID 1ft1 , 1ft2 , 1d8e
Descriptor farnesyltranserase (alpha subunit)/farnesyltranserase (beta subunit)/K-RAS4B PEPTIDE SUBSTRATE
Title CO-CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A K-RAS4B PEPTIDE SUBSTRATE AND FPP ANALOG AT 2.0A RESOLUTION
Functional Keywords FTASE, PFT, PFTASE, FARNESYLTRANSFERASE, FARNESYL TRANSFERASE, CAAX, RAS, CANCER
Biological source Rattus norvegicus
(Norway rat)
Cellular location
[UNP - P01116 ]
Cell membrane; Lipid-anchor; Cytoplasmic side
Organ source BRAIN
Total number of polymer chains 3
Total molecular weight 94781 (the details in Structural Details Page )
Authors Long, S.B. , Casey, P.J. , Beese, L.S.
(deposition date : 1999-10-22, release date : 2000-02-09)
Primary citation Long, S.B. , Casey, P.J. , Beese, L.S. The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 Angstroms resolution ternary complex structures.
Structure ,
8:209 - 222, 2000.(PubMed : 10673434) (DOI: 10.1016/S0969-2126(00)00096-4)
Experimental method X-RAY DIFFRACTION ( 2.00[Å] )
Other Database Information