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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID2q1b  sequence information (FASTA format)   
RELATED PDB ID1oq5, 1z9y
DescriptorCarbonic anhydrase 2 (E.C.4.2.1.1)
TitleCarbonic Anhydrase II in Complex with Saccharin
Functional Keywords10-STRANDED, TWISTED BETA-SHEET, LYASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - P00918] Cytoplasm
Organ source [UNP - P00918] Ovary
Total number of polymer chains1
Total molecular weight29926 (the details in Structural Details Page)
AuthorsKlebe, G. , Heine, A. , Koehler, K. (deposition date : 2007-05-24, release date : 2007-09-04)
Primary citationKohler, K. , Hillebrecht, A. , Schulze Wischeler, J. , Innocenti, A. , Heine, A. , Supuran, C.T. , Klebe, G.
Saccharin Inhibits Carbonic Anhydrases: Possible Explanation for its Unpleasant Metallic Aftertaste.
Angew.Chem.Int.Ed.Engl., 46:7697 - 7699, 2007.(PubMed : 17705204)  (DOI: 10.1002/anie.200701189)
Experimental methodX-RAY DIFFRACTION ( 1.70[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00918 ) , eF-site , KEGG ( EC 4.2.1.1 ) , PISA