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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID3bm8  sequence information (FASTA format)   
DescriptorTyrosine-protein phosphatase yopH (E.C.3.1.3.48)
Titlecrystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
Functional Keywordsco-valent binding, PVSN, binding selectivity, binding affinity, Hydrolase, Membrane, Outer membrane, Plasmid, Protein phosphatase, Secreted, Virulence
HYDROLASE
Biological sourceYersinia enterocolitica
Cellular location [UNP - P15273] Secreted
Total number of polymer chains1
Total molecular weight33563.1 (the details in Structural Details Page)
AuthorsZhang, Z.Y. , Liu, S.J. (deposition date : 2007-12-12, release date : 2008-06-17)
Primary citationLiu, S. , Zhou, B. , Yang, H. , He, Y. , Jiang, Z.X. , Kumar, S. , Wu, L. , Zhang, Z.Y.
Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130:8251 - 8260, 2008.(PubMed : 18528979)  (DOI: 10.1021/ja711125p)
Experimental methodX-RAY DIFFRACTION ( 2.7[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P15273 ) , eF-site , KEGG ( EC 3.1.3.48 ) , PISA