PDB ID 1dx6 sequence information (FASTA format)
RELATED PDB ID 2ace , 3ace , 4ace , 1acj , 2ack , 1acl , 1amn , 1fss , 1vot , 1ax9 , 1eve , 1cfj
Descriptor ACETYLCHOLINESTERASE (E.C.3.1.1.7)
Title STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-GALANTHAMINE AT 2.3A RESOLUTION
Functional Keywords HYDROLASE, SERINE HYDROLASE, CHOLINESTERASE, ALZHEIMER'S DISEASE
Biological source TORPEDO CALIFORNICA
(PACIFIC ELECTRIC RAY)
Cellular location
[UNP - P04058 ]
Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein
Organ source ELECTRIC ORGAN
Total number of polymer chains 2
Total molecular weight 62674.2 (the details in Structural Details Page )
Authors Greenblatt, H.M. , Kryger, G. , Lewis, T.T. , Silman, I. , Sussman, J.L.
(deposition date : 1999-12-21, release date : 2000-01-02)
Primary citation Greenblatt, H.M. , Kryger, G. , Lewis, T.T. , Silman, I. , Sussman, J.L. Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 angstroms resolution.
FEBS Lett. ,
463:321 - , 1999.(PubMed : 10606746) (DOI: 10.1016/S0014-5793(99)01637-3)
Experimental method X-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information