English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2a19  sequence information (FASTA format)   
RELATED PDB ID2a1a
DescriptorEukaryotic translation initiation factor 2 alpha subunit/ Interferon-induced, double-stranded RNA-activated protein kinase (E.C.2.7.1.-)
TitlePKR kinase domain- eIF2alpha- AMP-PNP complex.
Functional Keywordstransferase, kinase, protein biosynthesis, protein synthesis/transferase COMPLEX
Biological sourceSaccharomyces cerevisiae (baker's yeast) ,Homo sapiens (human) (the details in Structural Details Page)
Organ source [UNP - P19525] Placenta
[UNP - P19525] Brain
Total number of polymer chains3
Total molecular weight87358.1 (the details in Structural Details Page)
AuthorsDar, A.C. , Dever, T.E. , Sicheri, F. (deposition date : 2005-06-19, release date : 2005-09-27)
Primary citationDar, A.C. , Dever, T.E. , Sicheri, F.
Higher-Order Substrate Recognition of eIF2alpha by the RNA-Dependent Protein Kinase PKR.
Cell(Cambridge,Mass.), 122:887 - 900, 2005.(PubMed : 16179258)  (DOI: 10.1016/j.cell.2005.06.044)
Experimental methodX-RAY DIFFRACTION ( 2.50[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P20459, P19525 ) , eF-site , PISA