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MineSummary [3ivt]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID3ivt  sequence information (FASTA format)   
RELATED PDB ID3ivs, 3ivu
DescriptorHomocitrate synthase, mitochondrial (E.C.2.3.3.14)
TitleHomocitrate Synthase Lys4 bound to 2-OG
Functional KeywordsTIM barrel, Metalloprotein, Transferase, Claisen condensation, Amino-acid biosynthesis, Lysine biosynthesis, Mitochondrion, Transit peptide
TRANSFERASE
Biological sourceSchizosaccharomyces pombe (Fission yeast)
Cellular location [UNP - Q9Y823] Mitochondrion (Potential)
Total number of polymer chains2
Total molecular weight93979.8 (the details in Structural Details Page)
AuthorsBulfer, S.L. , Scott, E.M. , Couture, J-F. , Pillus, L. , Trievel, R.C. (deposition date : 2009-09-01, release date : 2009-09-22)
Primary citationBulfer, S.L. , Scott, E.M. , Couture, J.F. , Pillus, L. , Trievel, R.C.
Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis.
J.Biol.Chem., 284:35769 - 35780, 2009.(PubMed : 19776021)  (DOI: 10.1074/jbc.M109.046821)
Experimental methodX-RAY DIFFRACTION ( 2.670[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9Y823 ) , eF-site , KEGG ( EC 2.3.3.14 ) , PISA