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[3mi3] replaced from '3l90'

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID3mi3  sequence information (FASTA format)   
RELATED PDB ID3ivs, 3ivt, 3ivu
DescriptorHomocitrate synthase, mitochondrial (E.C.2.3.3.14)
TitleHomocitrate Synthase Lys4 bound to Lysine
Functional KeywordsTIM barrel, Metalloprotein, Transferase, Claisen condensation, Amino-acid biosynthesis, lysine biosynthesis
Amino-acid biosynthesis, lysine biosynthesis, Transferase
Biological sourceSchizosaccharomyces pombe (Fission yeast)
Cellular location [UNP - Q9Y823] Mitochondrion (Potential)
Total number of polymer chains2
Total molecular weight93982 (the details in Structural Details Page)
AuthorsBulfer, S.L. , Scott, E.M. , Pillus, L. , Trievel, R.C. (deposition date : 2010-04-09, release date : 2010-04-28)
Primary citationBulfer, S.L. , Scott, E.M. , Pillus, L. , Trievel, R.C.
Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase
J.Biol.Chem., 285:10446 - 10453, 2010.(PubMed : 20089861)
Experimental methodX-RAY DIFFRACTION ( 2.380[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9Y823 ) , eF-site , KEGG ( EC 2.3.3.14 ) , PISA