PDB ID 3mi3 sequence information (FASTA format)
RELATED PDB ID 3ivs , 3ivt , 3ivu
Descriptor Homocitrate synthase, mitochondrial (E.C.2.3.3.14)
Title Homocitrate Synthase Lys4 bound to Lysine
Functional Keywords TIM barrel, Metalloprotein, Transferase, Claisen condensation, Amino-acid biosynthesis, lysine biosynthesis Amino-acid biosynthesis, lysine biosynthesis, Transferase
Biological source Schizosaccharomyces pombe
(Fission yeast)
Cellular location
[UNP - Q9Y823 ]
Mitochondrion (Potential)
Total number of polymer chains 2
Total molecular weight 93982 (the details in Structural Details Page )
Authors Bulfer, S.L. , Scott, E.M. , Pillus, L. , Trievel, R.C.
(deposition date : 2010-04-09, release date : 2010-04-28)
Primary citation Bulfer, S.L. , Scott, E.M. , Pillus, L. , Trievel, R.C. Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase
J.Biol.Chem. ,
285:10446 - 10453, 2010.(PubMed : 20089861)
Experimental method X-RAY DIFFRACTION ( 2.380[Å] )
Other Database Information