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<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1fq4  sequence information (FASTA format)   
RELATED PDB ID2jxr, 1dpj, 1fq5, 1fq6, 1fq7, 1fq8
DescriptorSACCHAROPEPSIN (E.C.3.4.23.25)
TitleCRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A
Functional KeywordsAspartic proteinase/inhibitor complex, extended beta-strand (inhibitor), HYDROLASE
Biological sourceSaccharomyces cerevisiae (baker's yeast)
Cellular location [UNP - P07267] Vacuole
Total number of polymer chains2
Total molecular weight37601.8 (the details in Structural Details Page)
AuthorsCronin, N.B. , Badasso, M.O. , Tickle, I.J. , Dreyer, T. , Hoover, D.J. , Rosati, R.L. , Humblet, C.C. , Lunney, E.A. , Cooper, J.B. (deposition date : 2000-09-03, release date : 2000-09-20)
Primary citationCronin, N.B. , Badasso, M.O. , J Tickle, I. , Dreyer, T. , Hoover, D.J. , Rosati, R.L. , Humblet, C.C. , Lunney, E.A. , Cooper, J.B.
X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J. Mol. Biol., 303:745 - 760, 2000.(PubMed : 11061973)  (DOI: 10.1006/jmbi.2000.4181)
Experimental methodX-RAY DIFFRACTION ( 2.7[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P07267 ) , eF-site , KEGG ( EC 3.4.23.25 ) , PISA