PDB ID 1fq4 sequence information (FASTA format)
RELATED PDB ID 2jxr , 1dpj , 1fq5 , 1fq6 , 1fq7 , 1fq8
Descriptor SACCHAROPEPSIN (E.C.3.4.23.25)
Title CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A
Functional Keywords Aspartic proteinase/inhibitor complex, extended beta-strand (inhibitor), HYDROLASE
Biological source Saccharomyces cerevisiae
(baker's yeast)
Cellular location
[UNP - P07267 ]
Vacuole
Total number of polymer chains 2
Total molecular weight 37601.8 (the details in Structural Details Page )
Authors Cronin, N.B. , Badasso, M.O. , Tickle, I.J. , Dreyer, T. , Hoover, D.J. , Rosati, R.L. , Humblet, C.C. , Lunney, E.A. , Cooper, J.B.
(deposition date : 2000-09-03, release date : 2000-09-20)
Primary citation Cronin, N.B. , Badasso, M.O. , J Tickle, I. , Dreyer, T. , Hoover, D.J. , Rosati, R.L. , Humblet, C.C. , Lunney, E.A. , Cooper, J.B. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J. Mol. Biol. ,
303:745 - 760, 2000.(PubMed : 11061973) (DOI: 10.1006/jmbi.2000.4181)
Experimental method X-RAY DIFFRACTION ( 2.7[Å] )
Other Database Information