Gene information | Cerebellar Development Transcriptome Database (CDT-DB)

19690176 Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver
18764764 Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase
18554416 Identification of transcripts with enriched expression in the developing and adult pancreas
18466336 Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid
17990318 Vitamin C supplementation does not protect L-gulono-gamma-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy

Show all (10) references (detailed information)

CD gene Number	CD41137
Gene Symbol	Gulo
Gene description	gulonolactone (L-) oxidase
Alternative name(s)	L-gulonolactone oxidase; GLO; LGO; L-gulono-gamma-lactone oxidase
Alternative name(s)	sfx, unh, unhip, AU018375, BC028822, MGC29968, MGC37793, MGC37880, 5730581M22
Accession ID	NM_178747
Gene Category
Gene Ontology	biological_process biosynthetic process , L-ascorbic acid biosynthetic process , oxidation reduction cellular_component endoplasmic reticulum , integral to membrane , membrane , microsome molecular_function catalytic activity , D-arabinono-1,4-lactone oxidase activity , FAD binding , L-gulonolactone oxidase activity , oxidoreductase activity , oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor ... [Show All]
Temporal expression	up regulation
Spatial expression (characteristic site)	P7 : P21 :
Brain distribution (characteristic site)	P7 : P21 :
Brain specificity
Experimental data	Temporal Tissue
Probe	CDT EST : Affymetrix : 1451297_at (MG 430 2.0 Array)
Links	General information Entrez Gene : 268756 MGI : 1353434 Ensembl : ENSMUSG00000034450 UniGene : Mm.26207 OMIM : 240400 GEO : Gulo KEGG : Ascorbate and aldarate metabolism 00053, Metabolic pathways 01100 Genome information Harvester UCSC Mouse Genome Browser Gateway Perlegen/NIEHS Mouse Genome Browser Functional genomics GeneNetwork Mouse Phenome Database BioGPS STRING Nervous system SynDB Mouse Neuronal Expression Database Reference information GoPubMed iHOP PubMed Spatial information ABA GenePaint BGEM
References	19690176 Beta-catenin regulates vitamin C biosynthesis and cell survival in murine liver 18764764 Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase 18554416 Identification of transcripts with enriched expression in the developing and adult pancreas 18466336 Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid 17990318 Vitamin C supplementation does not protect L-gulono-gamma-lactone oxidase-deficient mice from Helicobacter pylori-induced gastritis and gastric premalignancy Show all (10) references (detailed information)