InterProInterPro Protein Domain record

Ornithine aminotransferase
http://metadb.riken.jp/db/SciNetS_rib124i/crib124s1rib124u10164i

Ornithine aminotransferase

InterPro Protein Domain record

description
  • <p>Ornithine aminotransferase catalyses the conversion of L-ornithine and a 2-oxo acid to L-glutamate 5-semialdehyde and an L-amino acid. This enzyme is found in low-GC bacteria, where it is responsible for the fourth step in arginine biosynthesis, and in the mitochondrial matrix of eukaryotes, where it controls L-ornithine levels in tissues. In human hereditary ornithine aminotransferase deficiency, the elevated levels of intraocular concentrations of ornithine are responsible for gyrate atrophy, which affects the CNS and peripheral nervous system [<cite idref="PUB00014863"/>].</p>
label
  • Ornithine aminotransferase
attributionURL
signatures_SMART
type
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contains
PDB_structure
InterPro Protein Domain record
Os_RAPDB_Locus