<p>This entry describes the anti-sigma B factor also known as serine-protein kinase RsbW. Sigma B controls the general stress regulon in B subtilis and is activated by cell stresses such as stationary phase and heat shock. RsbW binds to sigma B and prevents formation of the transcription complex at the promoter [<cite idref="PUB00013752"/>]. RsbV (anti-anti-sigma factor) binds to RsbW to inhibit association with sigma B, however RsbW can phosphorylate RsbV, causing disassociation of the RsbV/RsbW complex [<cite idref="PUB00013851"/>]. Low ATP level or environmental stress causes the dephosphorylation of RsbV [<cite idref="PUB00013846"/>].</p>