<p> <taxon tax_id="4932">Saccharomyces cerevisiae</taxon> Nse1 (<db_xref db="SWISSPROT" dbkey="Q07913"/>) forms part of a complex with SMC5-SMC6. This non-structural maintenance of chromosomes (SMC) complex plays an essential role in genomic stability, being involved in DNA repair and DNA metabolism [<cite idref="PUB00014740"/>, <cite idref="PUB00014741"/>]. It is conserved in eukaryotes from yeast to human.</p>