InterProInterPro Protein Domain record

DNA mismatch repair protein, N-terminal
http://metadb.riken.jp/db/SciNetS_rib124i/crib124s1rib124u14763i

DNA mismatch repair protein, N-terminal

InterPro Protein Domain record

description
  • <p>This entry represents DNA mismatch repair proteins, such as MutL. The dimeric MutL protein has a key function in communicating mismatch recognition by MutS to downstream repair processes. Mismatch repair contributes to the overall fidelity of DNA replication by targeting mispaired bases that arise through replication errors during homologous recombination and as a result of DNA damage. It involves the correction of mismatched base pairs that have been missed by the proofreading element of the DNA polymerase complex [<cite idref="PUB00020815"/>].</p>
label
  • DNA mismatch repair protein, N-terminal
attributionURL
signatures_SMART
type
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InterPro Protein Domain record