<p>Ribosomal protein S5 is one of the proteins from the small ribosomal subunit, and is a protein of 166 to 254 amino-acid residues. In <taxon tax_id="562">Escherichia coli</taxon>, S5 is known to be important in the assembly and function of the 30S ribosomal subunit. Mutations in S5 have been shown to increase translational error frequencies. It belongs to a family of ribosomal proteins which, on the basis of sequence similarities [<cite idref="PUB00005070"/>, <cite idref="PUB00003665"/>], groups bacterial, cyanelle, red algal chloroplast, archaeal and fungal mitochondrial S5; mammalian, <taxon tax_id="6239">Caenorhabditis elegans</taxon>, Drosophila and plant S2; and yeast S4 (SUP44).</p><p>This entry represents the conserved site of the ribosomal protein S5. </p><p>This entry represents the N-terminal domain of ribosomal protein S5, which has an alpha-beta(3)-alpha structure that folds into two layers, alpha/beta.</p>