This family of proteins are related to a large superfamily of metalloenzymes [<cite idref="PUB00004994"/>]. TatD, a member of this family has been shown experimentally to be a DNase enzyme [<cite idref="PUB00007123"/>]. Allantoinase <db_xref db="EC" dbkey="3.5.2.5"/>, N-isopropylammelide isopropyl amidohydrolase <db_xref db="EC" dbkey="3.5.1"/> and the SCN1 protein from fission yeast belong to this family.