During the process of <taxon tax_id="562">Escherichia coli</taxon> nucleotide excision repair, DNA damagerecognition and processing are achieved by the action of the uvrA, uvrB,and uvrC gene products [<cite idref="PUB00006064"/>]. UvrB and UvrC share a common domain of around 35amino acids, the so called UVR domain. This domain in UvrB can interact withthe homologous domain in UvrC throughout a putative coiled coil structure.This interaction is important for the incision of the damaged strand [<cite idref="PUB00006065"/>].