InterProInterPro Protein Domain record

Micronemal adhesive repeat, sialic-acid binding
http://metadb.riken.jp/db/SciNetS_rib124i/crib124s1rib124u19562i

Micronemal adhesive repeat, sialic-acid binding

InterPro Protein Domain record

description
  • <p> This entry represents a novel carbohydrate-binding domain found on micronemal proteins. Micronemal proteins (MICs) are released onto the parasite surface just before invasion of host cells and play important roles in host cell recognition, attachment and penetration. <taxon tax_id="5811">Toxoplasma gondii</taxon> can infect and replicate within all nucleated cells [<cite idref="PUB00044345"/>]. This domain interacts with sialylated oligosaccharides; the protein in T. gondii is a monomer but several MAR domains are carried on the protein. Each MAR domain contains one central sialic acid-binding pocket [<cite idref="PUB00044346"/>]. </p>
label
  • Micronemal adhesive repeat, sialic-acid binding
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InterPro Protein Domain record
Pfam-A