<p>Pyridoxamine 5'-phosphate oxidase (<db_xref db="EC" dbkey="1.4.3.5"/>) is a FMN flavoprotein involved in the de novo synthesisof pyridoxine (vitamin B6) and pyridoxal phosphate. It oxidizes pyridoxamine-5-P (PMP) and pyridoxine-5-P(PNP) to pyridoxal-5-P. The sequences of the enzyme from bacterial (genes pdxH or fprA) [<cite idref="PUB00002199"/>] andfungal (gene PDX3) [<cite idref="PUB00002264"/>] sources show that this protein has been highly conserved throughoutevolution. PdxH is evolutionary related [<cite idref="PUB00001735"/>] to one of the enzymes in the phenazine biosynthesisprotein pathway, phzD (also known as phzG).</p><p>This entry represents a highly conserved region located in the C-terminal part of these enzymes. </p>