<p>DNA primase [<cite idref="PUB00005693"/>] synthesizes the RNA primers for the Okazaki fragments in lagging strand DNA synthesis. DNA primase is a heterodimer of large (p60) and small (p50) subunits in eukaryotes. This family represents sequences of the small subunit and the DNA primase sequences of the Archaea [<cite idref="PUB00009771"/>]. No sequence similarity can be detected between the eukaryotic p50 and p60 subunits and the primases purified from bacteriophage and bacteria, <db_xref db="INTERPRO" dbkey="IPR006295"/>. </p><p>This entry represents the archaeal proteins.</p>