PfamPfam-A

MutL_C
http://metadb.riken.jp/db/SciNetS_rib125i/crib125s1rib125u8676i

MutL_C

Pfam-A

definition
  • MutL C terminal dimerisation domain
description
  • MutL and MutS are key components of the DNA repair machinerythat corrects replication errors [1]. MutS recognises mispairedor unpaired bases in a DNA duplex and in the presence of ATP,recruits MutL to form a DNA signaling complex for repair. The Nterminal region of MutL contains the ATPase domain and the Cterminal is involved in dimerisation [3].
label
  • MutL_C
attributionURL
InterPro entry
seeAlso
Domain Annotation(A.thaliana)