Tatsuro IRIMURA Mgl2 gene knockout mice. Exon 2 of the Mgl2 was replaced with a PGK-neo cassette. The MGL is one of the calcium-dependent (C type) lectins, which are intrinsic carbohydrate recognition proteins. Homozygous mutant mice are viable and fertile. Under investigation (details unknown). C57BL/6 background (RBRC01893) and BALB/c background (RBRC01894). Univ. Tokyo 国立大学法人東京大学 mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, bovine growth hormone poly A, mouse Mgl2 genomic DNA RBRC01894 東京大学薬学系研究科・入村達郎。TT2 ES細胞を用いて作出。C57BL/6JおよびBALB/cへ戻し交配された（RBRC01893およびRBRC01894）。 <a href="https://mus.brc.riken.jp/ja/wp-content/uploads/pdf/blc/01894_GB.pdf">Genetic Background</a> mMgl2 knockout mice (BALB/c) 条件を付加する。利用者は事前に寄託者の提供承諾書を得る。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。<br>研究成果の公表にあたって謝辞の表明を必要とする。<br>リソースの利用にあたっては、寄託者との共同研究とする。 true 入村　達郎 C.Cg-Mgl2<tm1Tats>/TatsRbrc Necessary documents for ordering:<ol><li>Approval form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx">English</A>)</li><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol><A HREF="https://www.juntendo.ac.jp/graduate/laboratory/labo/glyco/" target="_blank">Lab HP</A> mMgl2 knockout mice (BALB/c) mMgl2 knockout mice (BALB/c) Mgl2遺伝子の第2エクソンをネオマイシン耐性遺伝子で置換したもの。MGLは内在性糖鎖認識タンパク分子であるカルシウム依存型 (C型) レクチンのひとつ。ホモマウスは生存性、妊性有り。解析途上。C57BL/6背景 (RBRC01893) およびBALB/c背景 (RBRC01894) 。, C（3〜6か月） Homozygote x Homozygote [or Crossing to BALB/cAnNCrlCrlj] Homozygote x Homozygote [or Crossing to BALB/cAnNCrlCrlj] eveloped by Kaori Denda and Tasturo Irimura, Graduate School of Pharmaceutical Sciences, The University of Tokyo. TT2 ES cells derived from B6CBAF1 were used to generate the knockout mice. The mice were backcrossed to C57BL/6J and BALB/c, respectively (RBRC01893 and RBRC01894). <a href='https://brc.riken.jp/mus/pcr01894'>Genotyping protocol -PCR-</a> C (3-6 months) Mgl2遺伝子の第2エクソンをネオマイシン耐性遺伝子で置換したもの。MGLは内在性糖鎖認識タンパク分子であるカルシウム依存型 (C型) レクチンのひとつ。ホモマウスは生存性、妊性有り。解析途上。C57BL/6背景 (RBRC01893) およびBALB/c背景 (RBRC01894) 。 The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]