B6. Zkscan6 KO B6. Zkscan6 KO true C(3〜6か月) <a href='https://brc.riken.jp/mus/pcr09700'>Genotyping protocol -PCR-</a> 条件を付加しない。 No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) 東京大学・青木不学、Helena Fulkova(2016)により開発。C57BL/6Nの受精卵を使用。C57BL/6N背景。 ゲノム編集技術により作製されたZkscan6 (zinc finger with KRAB and SCAN domains 6) 変異マウス。エキソン3に2 bpの欠損があり、フレームシフト変異が起きる。ホモマウスは正常に生まれ、繁殖も可能。ホモマウスは尾がジグザグに曲がるkinked tailの特性を持つ。7 bp欠損の系統がRBRC9701として利用可能。 RBRC09700 Zkscan6 (zinc finger with KRAB and SCAN domains 6) mutant mice generated by the Genome editing technique (CRISPR/Cas9). This mutant contains 2 bp deletion at exon 3 of the Zkscan6 gene causing a frameshift. Homozygous mutants are viable and fertile. 7 bp deletion mutant of Zkscan6 is also available in RBRC09701. C (3-6 months) Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: CRISPR/Cas9 genome edited bioresources (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/Broad_MTA_J.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/Broad_MTA_E.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> C57BL/6N-Zkscan6<em1Ibbr> C57BL/6N-Zkscan6<em1Ibbr> Developed by Fugaku Aoki and Helena Fulkova, The University of Tokyo in 2016. Fertilized eggs derived from C57BL/6N were used. C57BL/6N background.