English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1hkn  sequence information (FASTA format)   
RELATED PDB ID1axm, 1djs, 1dzc, 1dzd, 1e0o, 1evt, 1jqz, 1jt3, 1jt4, 1jt5, 1jt7, 1jtc, 1k5u, 1k5v, 1qct, 1rml, 2afg, 2axm
DescriptorHEPARIN-BINDING GROWTH FACTOR 1
TitleA COMPLEX BETWEEN ACIDIC FIBROBLAST GROWTH FACTOR AND 5-AMINO-2-NAPHTHALENESULFONATE
Functional KeywordsGROWTH FACTOR, MITOGEN, ANGIOGENESIS, HEPARIN-BINDING
Biological sourceHOMO SAPIENS (HUMAN)
Organ source [UNP - P05230] Brain stem
[UNP - P05230] Liver
Total number of polymer chains6
Total molecular weight94711.2 (the details in Structural Details Page)
AuthorsFernandez-Tornero, C. , Lozano, R.M. , Gimenez-Gallego, G. , Romero, A. (deposition date : 2003-03-10, release date : 2004-03-11)
Primary citationFernandez-Tornero, C. , Lozano, R.M. , Redondo-Horcajo, M. , Gomez, A.M. , Lopez, J.C. , Quesada, E. , Uriel, C. , Valverde, S. , Cuevas, P. , Romero, A. , Gimenez-Gallego, G.
Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J. Biol. Chem., 278:21774 - 21781, 2003.(PubMed : 12676958)  (DOI: 10.1074/JBC.M212833200)
Experimental methodX-RAY DIFFRACTION ( 2.00[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P05230 ) , eF-site , PISA