English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1hl2  sequence information (FASTA format)   
RELATED PDB ID1fdy, 1fdz, 1nal
DescriptorN-ACETYLNEURAMINATE LYASE SUBUNIT (E.C.4.1.3.3)
TitleCRYSTAL STRUCTURE OF N-ACETYLNEURAMINATE LYASE FROM E. COLI MUTANT L142R IN COMPLEX WITH B-HYDROXYPYRUVATE
Functional KeywordsN-ACETYLNEURAMINATE LYASE, CLASS I ALDOLASE, LYASE, CARBOHYDRATE METABOLISM, SCHIFF BASE
Biological sourceESCHERICHIA COLI
Total number of polymer chains4
Total molecular weight131099.2 (the details in Structural Details Page)
AuthorsJoerger, A.C. , Fersht, A.R. (deposition date : 2003-03-12, release date : 2003-05-09)
Primary citationJoerger, A.C. , Mayer, S. , Fersht, A.R.
Mimicking Natural Evolution in Vitro: An N-Acetylneuraminate Lyase Mutant with an Increased Dihydrodipicolinate Synthase Activity
Proc. Natl. Acad. Sci. U.S.A., 100:5694 - , 2003.(PubMed : 12711733)  (DOI: 10.1073/PNAS.0531477100)
Experimental methodX-RAY DIFFRACTION ( 1.8[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , eF-site , KEGG ( EC 4.1.3.3 ) , PISA