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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1i7r  sequence information (FASTA format)   
RELATED PDB ID1i7t, 1i7u
DescriptorHLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2-MICROGLOBULIN
TitleCRYSTAL STRUCTURE OF CLASS I MHC A2 IN COMPLEX WITH PEPTIDE P1058
Functional KeywordsMHC fold, IMMUNE SYSTEM
Biological sourceHomo sapiens (human)
Cellular location [UNP - P01892] Membrane; Single-pass type I membrane protein
[UNP - P61769] Secreted
Organ source [UNP - P01892] Blood
[UNP - P01892] Platelet
[UNP - P61769] Peripheral blood
[UNP - P61769] Dendritic cell
[UNP - P61769] Leukemia
[UNP - P61769] Trachea
[UNP - P61769] Eye, and Skin
[UNP - P61769] Urine
Total number of polymer chains6
Total molecular weight89584.4 (the details in Structural Details Page)
AuthorsBusslep, J. , Zhao, R. , Loftus, D. , Appella, E. , Collins, E.J. (deposition date : 2001-03-10, release date : 2001-10-24)
Primary citationBusslep, J. , Zhao, R. , Donnini, D. , Loftus, D. , Saad, M. , Appella, E. , Collins, E.J.
T cell activity correlates with oligomeric peptide/MHC binding on T cell surface
J.Biol.Chem., 276:47320 - 47328, 2001.(PubMed : 11584024)  (DOI: 10.1074/jbc.M109231200)
Experimental methodX-RAY DIFFRACTION ( 2.2[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01892, P61769 ) , eF-site , PISA