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MineSummary [1iar]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1iar  sequence information (FASTA format)   
DescriptorINTERLEUKIN-4, INTERLEUKIN-4 RECEPTOR ALPHA CHAIN
TitleINTERLEUKIN-4 / RECEPTOR ALPHA CHAIN COMPLEX
Functional KeywordsCYTOKINE RECEPTOR,INTERLEUKIN-4, CYTOKINE/RECEPTOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P05112] Secreted
[UNP - P24394] Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted
Organ source [UNP - P05112] Blood
[UNP - P24394] Peripheral blood
[UNP - P24394] Myeloid leukemia cell
Total number of polymer chains2
Total molecular weight38728.2 (the details in Structural Details Page)
AuthorsHage, T. , Sebald, W. , Reinemer, P. (deposition date : 1999-02-25, release date : 2000-03-03)
Primary citationHage, T. , Sebald, W. , Reinemer, P.
Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface.
Cell(Cambridge,Mass.), 97:271 - 281, 1999.(PubMed : 10219247)  (DOI: 10.1016/S0092-8674(00)80736-9)
Experimental methodX-RAY DIFFRACTION ( 2.3[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P05112, P24394 ) , eF-site , PISA