PDB ID 1ibc sequence information (FASTA format)
Descriptor INTERLEUKIN-1BETA CONVERTING ENZYME, PEPTIDE ACE-TRP-GLU-HIS-ASP
Title CRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME
Functional Keywords PROTEASE, CYSTEINE PROTEASE, INTERLEUKIN-1BETA CONVERTING ENZYME, ICE, CASPASE-1, COMPLEX (HYDROLASE/PEPTIDE)
Biological source Homo sapiens
(human)
Cellular location
[UNP - P29466 ]
Cytoplasm
Organ source
[UNP - P29466 ]
Testis
Total number of polymer chains 3
Total molecular weight 32310.1 (the details in Structural Details Page )
Authors Becker, J.W. , Rotonda, J.
(deposition date : 1997-02-12, release date : 1998-02-11)
Primary citation Rano, T.A. , Timkey, T. , Peterson, E.P. , Rotonda, J. , Nicholson, D.W. , Becker, J.W. , Chapman, K.T. , Thornberry, N.A. A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE).
Chem.Biol. ,
4:149 - 155, 1997.(PubMed : 9190289) (DOI: 10.1016/S1074-5521(97)90258-1)
Experimental method X-RAY DIFFRACTION ( 2.73[Å] )
Other Database Information