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<Asymmetric unit>

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<Biological unit>
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PDB ID1ibc  sequence information (FASTA format)   
DescriptorINTERLEUKIN-1BETA CONVERTING ENZYME, PEPTIDE ACE-TRP-GLU-HIS-ASP
TitleCRYSTAL STRUCTURE OF INHIBITED INTERLEUKIN-1BETA CONVERTING ENZYME
Functional KeywordsPROTEASE, CYSTEINE PROTEASE, INTERLEUKIN-1BETA CONVERTING ENZYME, ICE, CASPASE-1, COMPLEX (HYDROLASE/PEPTIDE)
Biological sourceHomo sapiens (human)
Cellular location [UNP - P29466] Cytoplasm
Organ source [UNP - P29466] Testis
Total number of polymer chains3
Total molecular weight32310.1 (the details in Structural Details Page)
AuthorsBecker, J.W. , Rotonda, J. (deposition date : 1997-02-12, release date : 1998-02-11)
Primary citationRano, T.A. , Timkey, T. , Peterson, E.P. , Rotonda, J. , Nicholson, D.W. , Becker, J.W. , Chapman, K.T. , Thornberry, N.A.
A combinatorial approach for determining protease specificities: application to interleukin-1beta converting enzyme (ICE).
Chem.Biol., 4:149 - 155, 1997.(PubMed : 9190289)  (DOI: 10.1016/S1074-5521(97)90258-1)
Experimental methodX-RAY DIFFRACTION ( 2.73[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P29466 ) , eF-site , KEGG ( EC 3.4.22.36 ) , PISA