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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1axe  sequence information (FASTA format)   
DescriptorALCOHOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL
TitleCRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL
Functional KeywordsOXIDOREDUCTASE (NAD(A)-CHOH(D)), ALCOHOL DEHYDROGENASE
Biological sourceEquus caballus (horse)
Cellular locationCYTOPLASM
Organ sourceLIVER
Total number of polymer chains2
Total molecular weight81573.8 (the details in Structural Details Page)
AuthorsColby, T.D. , Chin, J.K. , Goldstein, B.M. (deposition date : 1997-10-15, release date : 1998-04-15)
Primary citationBahnson, B.J. , Colby, T.D. , Chin, J.K. , Goldstein, B.M. , Klinman, J.P.
A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc. Natl. Acad. Sci. U.S.A., 94:12797 - 12802, 1997.(PubMed : 9371755)  (DOI: 10.1073/pnas.94.24.12797)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00327 ) , eF-site , KEGG ( EC 1.1.1.1 ) , PISA