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MineSummary [1ke3]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID1ke3  sequence information (FASTA format)   
RELATED PDB ID1c3b, 1ga9, 3bls, 1kds, 1kdw, 1ke0, 1ke4
Descriptorbeta-lactamase (E.C.3.5.2.6)
TitleX-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4,4'-biphenyldiboronic acid
Functional Keywordscephalosporinase, beta-lactamase, serine hydrolase, phenylboronic acid inhibitor
HYDROLASE
Biological sourceEscherichia coli
Cellular location [UNP - P00811] Periplasm
Total number of polymer chains2
Total molecular weight79755.2 (the details in Structural Details Page)
AuthorsPowers, R.A. , Shoichet, B.K. (deposition date : 2001-11-14, release date : 2002-07-17)
Primary citationPowers, R.A. , Shoichet, B.K.
Structure-based approach for binding site identification on AmpC beta-lactamase.
J.Med.Chem., 45:3222 - 3234, 2002.(PubMed : 12109906)  (DOI: 10.1021/jm020002p)
Experimental methodX-RAY DIFFRACTION ( 2.15[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00811 ) , eF-site , KEGG ( EC 3.5.2.6 ) , PISA