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MineSummary [2lef]

[2lef] replaced from '1lef'

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID2lef  sequence information (FASTA format)   
DescriptorPROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) MUTANT (CHAIN A, C25S)/DNA COMPLEX
TitleLEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES
Functional KeywordsLEF1, HMG, TCR-A, TRANSCRIPTION FACTOR, DNA BINDING, DNA BENDING, COMPLEX (HMG DOMAIN/DNA), GENE REGULATION/DNA COMPLEX
Biological sourceMus musculus (house mouse)
Cellular location [UNP - P27782] Nucleus
Total number of polymer chains3
Total molecular weight19582.4 (the details in Structural Details Page)
AuthorsLi, X. , Love, J.J. , Case, D.A. , Wright, P.E. (deposition date : 1998-10-13, release date : 1998-10-21)
Primary citationLove, J.J. , Li, X. , Case, D.A. , Giese, K. , Grosschedl, R. , Wright, P.E.
Structural basis for DNA bending by the architectural transcription factor LEF-1.
Nature, 376:791 - 795, 1995.(PubMed : 7651541)  (DOI: 10.1038/376791a0)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P27782 ) , eF-site , PISA , NRG-CING