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Summary [2fai]

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PDB ID or Keywordsequenceauthor name

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<Asymmetric unit> = <Biological unit> More images... View in 3D molecule viewer ( jV3 / Jmol ) *1

PDB ID 2fai  sequence information (FASTA format)    RELATED PDB ID 2b1v, 1zky Descriptor Estrogen receptor, Nuclear receptor coactivator 2 Title Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide Functional Keywords Estrogen Receptor, LBD, GRIP peptide, HORMONE/GROWTH FACTOR RECEPTOR COMPLEX Biological source Homo sapiens (human) Cellular location [UNP - P03372] Nucleus Organ source [UNP - P03372] Mammary gland [UNP - P03372] Mammary carcinoma [UNP - Q15596] Placenta [UNP - Q15596] Epithelium [UNP - Q15596] Testis Total number of polymer chains 4 Total molecular weight 62768.6 (the details in Structural Details Page) Authors Rajan, S.S. , Hsieh, R.W. , Sharma, S.K. , Greene, G.L. (deposition date : 2005-12-07, release date : 2006-05-09) Primary citation Hsieh, R.W. , Rajan, S.S. , Sharma, S.K. , Guo, Y. , Desombre, E.R. , Mrksich, M. , Greene, G.L. Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281:17909 - 17919, 2006.(PubMed : 16648639)  (DOI: 10.1074/jbc.M513684200) Experimental method X-RAY DIFFRACTION ( 2.10[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P03372, Q15596 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS

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