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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2fh5  sequence information (FASTA format)   
DescriptorSignal recognition particle receptor alpha subunit, Signal recognition particle receptor beta subunit
TitleThe Structure of the Mammalian SRP Receptor
Functional KeywordsEndomembrane targeting, GTPase, GAP, longin domain, SEDL, signal recognition particle receptor, X-ray structure, TRANSPORT PROTEIN
Biological sourceHomo sapiens (human) ,Mus musculus (house mouse) (the details in Structural Details Page)
Cellular location [UNP - P08240] Endoplasmic reticulum membrane; Peripheral membrane protein
[UNP - P47758] Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity)
Organ source [UNP - P08240] Amygdala
[UNP - P08240] Lung, Muscle, and Placenta
[UNP - P47758] Liver, Pancreas, Pituitary, Small intestine, and Testis
[UNP - P47758] Mammary gland
Total number of polymer chains2
Total molecular weight45414.4 (the details in Structural Details Page)
AuthorsSchlenker, O. , Wild, K. , Sinning, I. (deposition date : 2005-12-23, release date : 2006-01-31)
Primary citationSchlenker, O. , Hendricks, A. , Sinning, I. , Wild, K.
The structure of the mammalian signal recognition particle (SRP) receptor as prototype for the interaction of small GTPases with Longin domains.
J.Biol.Chem., 281:8898 - 8906, 2006.(PubMed : 16439358)  (DOI: 10.1074/jbc.M512415200)
Experimental methodX-RAY DIFFRACTION ( 2.45[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P08240, P47758 ) , eF-site , PISA