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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1o7s  sequence information (FASTA format)   
RELATED PDB ID1o7v
DescriptorSIALIC ACID BINDING IG-LIKE LECTIN 7
TitleHIGH RESOLUTION STRUCTURE OF SIGLEC-7
Functional KeywordsSIGLEC, IMMUNOGLOBULIN FOLD, SIALIC ACID BINDING PROTEIN, LECTIN, CELL ADHESION, IMMUNE SYSTEM
Biological sourceHOMO SAPIENS (HUMAN)
Cellular location [UNP - Q9Y286] Membrane; Single-pass type I membrane protein
Organ source [UNP - Q9Y286] Dendritic cell
[UNP - Q9Y286] Lymphoid
Total number of polymer chains1
Total molecular weight15219 (the details in Structural Details Page)
AuthorsAlphey, M.S. , Attrill, H. , Crocker, P.R. , Van Aalten, D.M.F. (deposition date : 2002-11-12, release date : 2003-03-30)
Primary citationAlphey, M.S. , Attrill, H. , Crocker, P.R. , van Aalten, D.M.F.
High Resolution Structures of Siglec-7 - Insights Into Ligand Specificity in the Siglec Family
J. Biol. Chem., 278:3372 - , 2003.(PubMed : 12438315)  (DOI: 10.1074/JBC.M210602200)
Experimental methodX-RAY DIFFRACTION ( 1.75[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q9Y286 ) , eF-site , PISA