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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1p0p  sequence information (FASTA format)   
RELATED PDB ID1p0i, 1p0m, 1p0q
DescriptorCholinesterase (E.C.3.1.1.8)
TitleCrystal structure of soman-aged human butyryl cholinesterase in complex with the substrate analog butyrylthiocholine
Functional KeywordsSerine hydrolase, organophosphates, soman, butyrylthiocholine, cholinesterase
HYDROLASE
Biological sourceHomo sapiens (human)
Organ source [UNP - P06276] Fetus
[UNP - P06276] Brain
[UNP - P06276] Stomach
[UNP - P06276] Skin
[UNP - P06276] Plasma
Total number of polymer chains3
Total molecular weight62047.3 (the details in Structural Details Page)
AuthorsNicolet, Y. , Lockridge, O. , Masson, P. , Fontecilla-Camps, J.C. , Nachon, F. (deposition date : 2003-04-10, release date : 2003-08-05)
Primary citationNicolet, Y. , Lockridge, O. , Masson, P. , Fontecilla-Camps, J.C. , Nachon, F.
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J. Biol. Chem., 278:41141 - 41147, 2003.(PubMed : 12869558)  (DOI: 10.1074/jbc.M210241200)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P06276 ) , eF-site , KEGG ( EC 3.1.1.8 ) , PISA