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MineSummary [1n83]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1n83  sequence information (FASTA format)   
DescriptorNuclear receptor ROR-alpha
TitleCrystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol
Functional Keywordsthree-layered alpha helical sandwich, receptor, transcription regulation, nuclear protein, DNA binding, LIPID BINDING PROTEIN
Biological sourceHomo sapiens (human)
Cellular location [UNP - P35398] Nucleus (Probable)
Organ source [UNP - P35398] Retina, and Testis
[UNP - P35398] Umbilical vein endothelial cell
[UNP - P35398] Muscle
Total number of polymer chains1
Total molecular weight31901.2 (the details in Structural Details Page)
AuthorsKallen, J.A. , Schlaeppi, J.M. , Bitsch, F. , Geisse, S. , Geiser, M. , Delhon, I. , Fournier, B. (deposition date : 2002-11-19, release date : 2002-12-11)
Primary citationKallen, J.A. , Schlaeppi, J.M. , Bitsch, F. , Geisse, S. , Geiser, M. , Delhon, I. , Fournier, B.
X-ray Structure of hROR(alpha) LBD at 1.63Å: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha)
Structure, 10:1697 - 1702, 2002.(PubMed : 12467577)  (DOI: 10.1016/S0969-2126(02)00912-7)
Experimental methodX-RAY DIFFRACTION ( 1.63[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P35398 ) , eF-site , PISA