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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1nez  sequence information (FASTA format)   
DescriptorH-2 class I histocompatibility antigen, TLA(C) alpha chain/Beta-2-microglobulin/T-cell surface glycoprotein CD8 alpha chain
TitleThe Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity
Functional KeywordsIMMUNE SYSTEM
Biological source [UNP - P14432] Mus musculus (Mouse)
Cellular location [UNP - P14432] Membrane; Single-pass type I membrane protein
[UNP - P01887] Secreted
Organ source [UNP - P01887] Liver
Total number of polymer chains4
Total molecular weight73045 (the details in Structural Details Page)
AuthorsLiu, Y. , Xiong, Y. , Naidenko, O.V. , Liu, J.H. , Zhang, R. , Joachimiak, A. , Kronenberg, M. , Cheroutre, H. , Reinherz, E.L. , Wang, J.H. (deposition date : 2002-12-12, release date : 2003-04-08)
Primary citationLiu, Y. , Xiong, Y. , Naidenko, O.V. , Liu, J.H. , Zhang, R. , Joachimiak, A. , Kronenberg, M. , Cheroutre, H. , Reinherz, E.L. , Wang, J.H.
The Crystal Structure of a TL/CD8alphaalpha Complex at 2.1 Å resolution: Implications for modulation of T cell activation and memory
Immunity, 18:205 - 215, 2003.(PubMed : 12594948)  (DOI: 10.1016/S1074-7613(03)00027-X)
Experimental methodX-RAY DIFFRACTION ( 2.1[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P14432, P01887, P01731 ) , eF-site , PISA