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MineSummary [1nrr]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID1nrr  sequence information (FASTA format)   
DescriptorALPHA-THROMBIN (E.C.3.4.21.5) NON-COVALENTLY COMPLEXED WITH RECEPTOR BASED PEPTIDE XA AND D-PHE-PRO-ARG CHLOROMETHYLKETONE (PPACK) WITH CHLOROMETHYLKETONE REPLACED BY A METHYLENE GROUP
TitleCRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Functional KeywordsSERINE PROTEINASE/RECEPTOR
Biological sourceHomo sapiens (human)
Cellular location [UNP - P00734] Secreted, extracellular space
[UNP - P25116] Cell membrane; Multi-pass membrane protein
Organ source [UNP - P00734] Mammary gland
[UNP - P00734] Plasma
[UNP - P25116] Eye
Total number of polymer chains4
Total molecular weight36636 (the details in Structural Details Page)
AuthorsTulinsky, A. , Mathews, I.I. (deposition date : 1994-01-18, release date : 1994-05-31)
Primary citationMathews, I.I. , Padmanabhan, K.P. , Ganesh, V. , Tulinsky, A. , Ishii, M. , Chen, J. , Turck, C.W. , Coughlin, S.R. , Fenton 2nd., J.W.
Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33:3266 - 3279, 1994.(PubMed : 8136362)  (DOI: 10.1021/bi00177a018)
Experimental methodX-RAY DIFFRACTION ( 2.4[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00734, P25116 ) , eF-site , KEGG ( EC 3.4.21.5 ) , PISA