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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1nx1  sequence information (FASTA format)   
RELATED PDB ID1nx0, 1nx2, 1nx3
DescriptorCalcium-dependent protease, small subunit (E.C.3.4.22.17)/calpastatin
TitleCalpain Domain VI Complexed with Calpastatin Inhibitory Domain C (DIC)
Functional KeywordsHYDROLASE, CALCIUM BINDING
Biological sourceSus scrofa (pig)
Cellular location [UNP - P04574] Cytoplasm (By similarity)
Total number of polymer chains4
Total molecular weight42396.4 (the details in Structural Details Page)
AuthorsTodd, B. , Moore, D. , Deivanayagam, C.C.S. , Lin, G.-D. , Chattopadhyay, D. , Maki, M. , Wang, K.K.W. , Narayana, S.V.L. (deposition date : 2003-02-07, release date : 2003-08-19)
Primary citationTodd, B. , Moore, D. , Deivanayagam, C.C.S. , Lin, G.D. , Chattopadhyay, D. , Maki, M. , Wang, K.K.W. , Narayana, S.V.L.
A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
J. Mol. Biol., 328:131 - 146, 2003.(PubMed : 12684003)  (DOI: 10.1016/S0022-2836(03)00274-2)
Experimental methodX-RAY DIFFRACTION ( 2.[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P04574, P49342 ) , eF-site , KEGG ( EC 3.4.22.17 ) , PISA