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<Asymmetric unit>

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PDB ID1p2o  sequence information (FASTA format)   
RELATED PDB ID1p2i, 1p2j, 1p2k, 1p2m, 1p2n, 1p2q
DescriptorChymotrypsinogen A (E.C.3.4.21.1), Pancreatic trypsin inhibitor
TitleStructural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
Functional Keywordstrypsin; chymotrypsin; serine proteinase; bovine pancreatic trypsin inhibitor; protein-protein interaction; non-cognate binding; S1 pocket; primary specificity; crystal structure, hydrolase/hydrolase inhibitor COMPLEX
Biological sourceBos taurus (cattle)
Cellular location [UNP - P00766] Secreted, extracellular space
[UNP - P00974] Secreted
Organ source [UNP - P00974] Adrenal chromaffin
Total number of polymer chains4
Total molecular weight64908 (the details in Structural Details Page)
AuthorsHelland, R. , Czapinska, H. , Leiros, I. , Olufsen, M. , Otlewski, J. , Smalaas, A.O. (deposition date : 2003-04-15, release date : 2004-04-20)
Primary citationHelland, R. , Czapinska, H. , Leiros, I. , Olufsen, M. , Otlewski, J. , Smalaas, A.O.
Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333:845 - 861, 2003.(PubMed : 14568540)  (DOI: 10.1016/j.jmb.2003.08.059)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00766, P00974 ) , eF-site , KEGG ( EC 3.4.21.1 ) , PISA