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<Asymmetric unit>
= <Biological unit>

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PDB ID1p6b  sequence information (FASTA format)   
DescriptorParathion hydrolase (E.C.3.1.8.1)
TitleX-ray structure of phosphotriesterase, triple mutant H254G/H257W/L303T
Functional Keywordsmetalloenzyme, tim barrel, nerve agents, HYDROLASE
Biological sourceFlavobacterium sp.
Cellular location [UNP - P0A433] Cell membrane; Peripheral membrane protein (By similarity)
Total number of polymer chains2
Total molecular weight73664.2 (the details in Structural Details Page)
AuthorsHill, C.M. , Li, W. , Thoden, J.B. , Holden, H.M. , Raushel, F.M. (deposition date : 2003-04-29, release date : 2003-09-16)
Primary citationHill, C.M. , Li, W.S. , Thoden, J.B. , Holden, H.M. , Raushel, F.M.
Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
J. Am. Chem. Soc., 125:8990 - 8991, 2003.(PubMed : 15369336)  (DOI: 10.1021/ja0358798)
Experimental methodX-RAY DIFFRACTION ( 1.90[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P0A433 ) , eF-site , KEGG ( EC 3.1.8.1 ) , PISA