PDB ID 1omw sequence information (FASTA format)
Descriptor Beta-adrenergic receptor kinase 1 (E.C.2.7.1.126), Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit
Title Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits
Functional Keywords WD-40 repeat, TRANSFERASE
Biological source Bos taurus
(cattle)
Cellular location
[UNP - P63212 ]
Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Organ source
[UNP - P62871 ]
Ascending colon
[UNP - P63212 ]
Adrenal gland, and Brain
[UNP - P63212 ]
Kidney
[UNP - P63212 ]
Brain
Total number of polymer chains 3
Total molecular weight 125574.6 (the details in Structural Details Page )
Authors Lodowski, D.T. , Pitcher, J.A. , Capel, W.D. , Lefkowitz, R.J. , Tesmer, J.J.G.
(deposition date : 2003-02-26, release date : 2003-06-03)
Primary citation Lodowski, D.T. , Pitcher, J.A. , Capel, W.D. , Lefkowitz, R.J. , Tesmer, J.J.G. Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma
Science ,
300:1256 - 1262, 2003.(PubMed : 12764189) (DOI: 10.1126/science.1082348)
Experimental method X-RAY DIFFRACTION ( 2.50[Å] )
Other Database Information