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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
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PDB ID1omw  sequence information (FASTA format)   
DescriptorBeta-adrenergic receptor kinase 1 (E.C.2.7.1.126), Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit
TitleCrystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits
Functional KeywordsWD-40 repeat, TRANSFERASE
Biological sourceBos taurus (cattle)
Cellular location [UNP - P63212] Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Organ source [UNP - P62871] Ascending colon
[UNP - P63212] Adrenal gland, and Brain
[UNP - P63212] Kidney
[UNP - P63212] Brain
Total number of polymer chains3
Total molecular weight125574.6 (the details in Structural Details Page)
AuthorsLodowski, D.T. , Pitcher, J.A. , Capel, W.D. , Lefkowitz, R.J. , Tesmer, J.J.G. (deposition date : 2003-02-26, release date : 2003-06-03)
Primary citationLodowski, D.T. , Pitcher, J.A. , Capel, W.D. , Lefkowitz, R.J. , Tesmer, J.J.G.
Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma
Science, 300:1256 - 1262, 2003.(PubMed : 12764189)  (DOI: 10.1126/science.1082348)
Experimental methodX-RAY DIFFRACTION ( 2.50[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P21146, P62871, P63212 ) , eF-site , KEGG ( EC 2.7.1.126 ) , PISA