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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1u0v  sequence information (FASTA format)   
RELATED PDB ID1u0w, 1u0u, 1bi5
DescriptorChalcone synthase 2 (E.C.2.3.1.74)
TitleAn Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization of Specificity of Type III Polyketide Synthases: 18xCHS structure
Functional Keywordstype III polyketide synthase, PKS, condensing enzyme, thiolase fold, alpha-beta-alpha-beta-alpha fold, aldol switch, catalytic triad, engineered resveratrol synthase, TRANSFERASE
Biological sourceMedicago sativa
Total number of polymer chains2
Total molecular weight85749.4 (the details in Structural Details Page)
AuthorsAustin, M.B. , Bowman, M.E. , Ferrer, J.-L. , Schroder, J. , Noel, J.P. (deposition date : 2004-07-14, release date : 2004-10-12)
Primary citationAustin, M.B. , Bowman, M.E. , Ferrer, J.-L. , Schroder, J. , Noel, J.P.
An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11:1179 - 1194, 2004.(PubMed : 15380179)  (DOI: 10.1016/j.chembiol.2004.05.024)
Experimental methodX-RAY DIFFRACTION ( 1.90[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P30074 ) , eF-site , KEGG ( EC 2.3.1.74 ) , PISA